A Simple One-step Synthesis of N-Substituted Isoindolin-1-ones. Diastereofacially Selective Protonation of an Intermediate Isoindolinol
α-Amino acids and their methyl esters, arylamines, heterocyclic amines and, less efficiently, aryl substituted aliphatic amines, react with o-phthaldialdehyde in the presence of acetic acid to give N-substituted isoindolin-1-ones in excellent yield; deute
Grigg, Ronald,Gunaratne, H. Q. Nimal,Sridharan, Visuvanathar
p. 1183 - 1184
(2007/10/02)
Synthesis of the 5H-Pyrroloisoindole Ring with 1,3-Dipolar Cycloaddition Reactions
The 1,3-dipolar cycloaddition reaction between mesoionic oxazolines, formed from either 1,3-dihydro-2-substituted-2H-isoindole-1-carboxylic acids or 1,3-dihydro-1-oxo-α-substituted-2H-isoindole-2-acetic acids, and dimethylacetylene dicarboxylate has led t
New, J. S.,Yevich, J. P.
p. 1355 - 1360
(2007/10/02)
New acylated derivatives of 2(4 aminophenyl)propionic acid as potential antiinflammatory agents
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Rufer,Bahlmann,Kapp
p. 193 - 198
(2007/10/06)
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