The first practical asymmetric synthesis of R and S-warfarin
A highly efficient synthesis of both enantiomers of warfarin Ia and Ib has been developed by using a novel two step 'chiral switch' strategy and a DuPHOS-Rh(I) catalyzed asymmetric hydrogenation.
Robinson, Andrea,Li, Hui-Yin,Feaster, John
p. 8321 - 8324
(2007/10/03)
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