676348-49-5

Basic information

• Product Name: (E)-3-(4-BROMO-2-FLUOROPHENYL)ACRYLOYL CHLORIDE
• Synonyms: 3-(4-BROMO-2-FLUORO-PHENYL)-ACRYLOYL CHLORIDE;(E)-3-(4-BROMO-2-FLUOROPHENYL)ACRYLOYL CHLORIDE
• CAS NO: 676348-49-5
• Molecular Formula: C9H5BrClFO
• Molecular Weight: 263.49
• Mol File: 676348-49-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (E)-3-(4-BROMO-2-FLUOROPHENYL)ACRYLOYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(4-BROMO-2-FLUOROPHENYL)ACRYLOYL CHLORIDE(676348-49-5)
• EPA Substance Registry System: (E)-3-(4-BROMO-2-FLUOROPHENYL)ACRYLOYL CHLORIDE(676348-49-5)

Safety Data

• Hazardous Substances Data: 676348-49-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(E)-3-(4-BROMO-2-FLUOROPHENYL)ACRYLOYL CHLORIDE is used as a building block in organic synthesis for the preparation of pharmaceuticals. Its unique structure and reactivity make it a valuable intermediate in the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
(E)-3-(4-BROMO-2-FLUOROPHENYL)ACRYLOYL CHLORIDE is also used as a building block in organic synthesis for the preparation of agrochemicals. Its properties allow for the creation of new compounds that can be used in the development of pesticides, herbicides, and other agricultural products to improve crop yields and protect against pests.

Upstream product

• 575469-65-7 3-(4-bromo-2-fluorophenyl)-2-propenoic acid 

Downstream Products

• 1588867-01-9 (E)-diisopropyl (3-(4-bromo-2-fluorophenyl)acryloyl)phosphonate 

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Compounds of formula (I): wherein R1, R2 and R3 are independently, hydrogen, halogen, CF3, OR6, NR7R8, NR8COR10, NR8SO2R10 or C1-6 alkyl optionally substituted by hydroxy, C1-6 alkoxy or NR7R8; R4 is NR8CONR8R9, NR8COR9, NR8SO2R9, or W-CONR8R9, where W is a bond, C1-6 alkylene, C2-6 alkenylene or C2-6 alkynylene; and R5 is Formula (A) methods for their synthesis, pharmaceutical compositions comprising them and their use in medicine, in particular for the treatment of cancer.