676495-94-6

Basic information

• Product Name: Piperidine, 3-(4-fluorophenyl)-
• Synonyms: Piperidine, 3-(4-fluorophenyl)-;3-(4-Fluorophenyl)piperidine
• CAS NO: 676495-94-6
• Molecular Formula: C₁₁H₁₄FN
• Molecular Weight: 179.23
• Mol File: 676495-94-6.mol

Chemical Properties

• Boiling Point: 262 ºC
• Flash Point: 112 ºC
• Appearance: /
• Density: 1.048
• Vapor Pressure: 0.0113mmHg at 25°C
• Refractive Index: 1.506
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: Piperidine, 3-(4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 3-(4-fluorophenyl)-(676495-94-6)
• EPA Substance Registry System: Piperidine, 3-(4-fluorophenyl)-(676495-94-6)

Safety Data

• Hazardous Substances Data: 676495-94-6(Hazardous Substances Data)

Usage

Uses

Used in Synthetic Chemistry:
Piperidine, 3-(4-fluorophenyl)is used as a building block or intermediate in the synthesis of more complex organic compounds. Its unique structure, including the 4-fluorophenyl group, allows for the creation of a variety of derivatives with different properties and potential applications.
Used in Pharmaceutical Research:
Piperidine, 3-(4-fluorophenyl)is used as a starting material or a component in the development of new pharmaceutical compounds. The presence of the fluorine atom in the phenyl ring can influence the compound's biological activity, making it a valuable candidate for drug discovery and design. Its potential applications in this field may include the development of new medications for various therapeutic areas.

InChI:InChI=1/C11H14FN/c12-11-5-3-9(4-6-11)10-2-1-7-13-8-10/h3-6,10,13H,1-2,7-8H2

Upstream product

• 85589-65-7 3-(4-fluorophenyl)pyridine 

Relevant articles and documents

Method for preparing piperidine compound by reducing pyridine compound through hydrogen transfer

The invention discloses a method for preparing a piperazine compound through a hydrogen transfer reduction of a pyridine compound, belonging to the field of organic synthesis. Under mild conditions, pyridine derivatives are used as raw materials, oxazolidine is used as a hydrogen transfer reagent, and cheap transition metals such as copper, cobalt, silver, palladium and the like are used as catalysts for catalysis of a hydrogen transfer reaction on 1,2,3,4-substitution sites, so a series of hydrogen transfer reduction product piperidine compounds are prepared, wherein the oxazaborolidine is obtained by a reaction of amino acid with a tetrahydrofuran complex of borane. The method has the advantages that product yield is high, reaction conditions are mild, the general applicability of raw materials is good, a hydrogen transfer reagent is cheap and easy to obtain, and good reproducibility can still be shown after quantitative reaction is conudcted. Therefore, the method of the invention provides an effective scheme for the industrial production of other high-value compounds containing the structure in the future.

QUATERNARY LACTAM COMPOUND AND PHARMACEUTICAL USE THEREOF

A quaternary lactam compound of formula (I). The compound is used in the manufacture of a medicament for the treatment and/or prevention of thrombotic or thromboembolic disorders.