Pyridine-3-carboxamides as novel CB2 agonists for analgesia
We describe herein the medicinal chemistry approach which led to the discovery of a novel pyridine-3-carboxamide series of CB2 receptor agonists. The SAR of this new template was evaluated and culminated in the identification of analogue 14a wh
Mitchell, William L.,Giblin, Gerard M.P.,Naylor, Alan,Eatherton, Andrew J.,Slingsby, Brian P.,Rawlings, Anthony D.,Jandu, Karamjit S.,Haslam, Carl P.,Brown, Andrew J.,Goldsmith, Paul,Clayton, Nick M.,Wilson, Alex W.,Chessell, Iain P.,Green, Richard H.,Whittington, Andrew R.,Wall, Ian D.
scheme or table
p. 259 - 263
(2009/05/26)
PYRIDINE DERIVATIVES AS CB2 RECEPTOR MODULATORS
The present invention relates to novel pyridine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease
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Page 46
(2010/02/06)
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