- Preparation of 3-methyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)pent-4-en-2-ol
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The invention provides a preparation method of 3-methyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-pent-4-en-2-ol. The preparation method comprises the following steps: firstly, converting a compound of astructure of a formula (III) shown in the description into a compound of a structure of a formula (IV) shown in the description, and further converting the compound of the structure of the formula (IV) into a compound of a structure of a formula (I) shown in the description. According to the preparation, the compound of the structure of the formula (III) is subjected to isomerization and methylation in a same reaction system to obtain the compound of the structure of the formula (IV), so that the obtained product is high in purity and high in yield, in addition, steps of reactions are simplified, and industrial production can be achieved.
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- Optical isomers of derivatives of campholenic aldehyde
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The present invention relates to a mixture of the 4 diastereomers 1'S,2R,3S; 1'S,2S,3R; 1'S,2S,3S and 1'S,2R,3R of (E)-3-methyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pent-4-en-2-ol, a mixture of the 4 diastereomers 1'R,2S,3R; 1'R,2R,3S; 1'R,2R,3R and 1'R,2S,3S of (E)-3-methyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pent-4-en-2-ol and to (1'S,2S,3R)-(E)-3-methyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pent-4-en-2-ol, (1'R,2S,3R)-(E)-3-methyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pent-4-en-2-ol and to a process for the manufacture of these compounds or mixtures. Further, the invention is related to any isomer mixture of (E)-3-methyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pent-4-en-2-ol enriched in one or both of the compounds or mixtures, especially to an odorant composition containing any isomer mixture of (E)-3-methyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pent-4-en-2-ol enriched in one or both of the above compounds or mixtures, and to the use of any one of the compounds or mixtures as odorants.
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- (2R*,3S*)-(E)-3-methyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pent-4-en-2-ol
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(2R*,3S*)-(E)-3-Methyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pent-4-en-2-ol possesses a very intense creamy, woody, musk, sandalwood odor and is a valuable ingredient for use in fragrance compositions for its musk and sandalwood-like qualities. This odorant is more intense than any of the campholenic aldehyde derivatives that have been previously reported.
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