680579-19-5

Basic information

• Product Name: 2-(1-TERT-BUTOXYCARBONYLPIPERAZIN-4-YL)PROPIONIC ACID
• Synonyms: RAC 2-(1-BOC-PIPERAZIN-4-YL)-PROPIONIC ACID;RAC 2-(1-TERT-BUTOXYCARBONYL-PIPERAZIN-4-YL)-PROPIONIC ACID;2-(1-TERT-BUTOXYCARBONYLPIPERAZIN-4-YL)PROPIONIC ACID;Rac 2-[4-(tert-butoxycarbonyl)piperazin-1-yl]propanoic acid;2-(Piperazin-1-yl)propionic acid, N4-BOC protected;RAC 2-(1-BOC-PIPERAZIN-4-YL)-PROPIONIC ACID, RAC 2-(1-TERT-BUTOXYCARBONYL-PIPERAZIN-4-YL)-PROPIONIC ACID >97%;N4-BOC-2-(PIPERAZIN-1-YL)PROPIONIC ACID;4-(1-Carboxyethyl)piperazine, N1-BOC protected
• CAS NO: 680579-19-5
• Molecular Formula: C12H22N2O4
• Molecular Weight: 258.31
• Product Categories: piperazines
• Mol File: 680579-19-5.mol

Chemical Properties

• Boiling Point: 372.923 °C at 760 mmHg
• Flash Point: 179.338 °C
• Appearance: /
• Density: 1.161 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.503
• CAS DataBase Reference: 2-(1-TERT-BUTOXYCARBONYLPIPERAZIN-4-YL)PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-TERT-BUTOXYCARBONYLPIPERAZIN-4-YL)PROPIONIC ACID(680579-19-5)
• EPA Substance Registry System: 2-(1-TERT-BUTOXYCARBONYLPIPERAZIN-4-YL)PROPIONIC ACID(680579-19-5)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 680579-19-5(Hazardous Substances Data)

Usage

Uses

Used in Organic Chemistry:
2-(1-Tert-Butoxycarbonylpiperazin-4-yl)propionic acid is used as a peptide synthesis intermediate for the protection of amine groups during the synthesis process. The Boc group's ability to shield amine groups is crucial in preventing unwanted side reactions, thereby facilitating the formation of desired peptide sequences.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-(1-Tert-Butoxycarbonylpiperazin-4-yl)propionic acid is employed as a building block for the development of new drugs. Its role in peptide synthesis allows for the creation of novel peptide-based therapeutics, which can be tailored for specific medical applications, such as the treatment of diseases or the enhancement of drug delivery systems.
Used in Chemical Research and Experiments:
2-(1-Tert-Butoxycarbonylpiperazin-4-yl)propionic acid is utilized as a versatile compound in chemical research, where its properties, such as density, boiling point, melting point, and flash point, make it suitable for a variety of experimental applications. Its intermediate role in organic synthesis provides opportunities for the exploration of new chemical reactions and the synthesis of complex molecules.

InChI:InChI=1/C12H22N2O4/c1-9(10(15)16)13-5-7-14(8-6-13)11(17)18-12(2,3)4/h9H,5-8H2,1-4H3,(H,15,16)

Upstream product

• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 900535-41-3 tert-butyl 4-(1-methoxy-1-oxopropan-2-yl)piperazine-1-carboxylate 

Downstream Products

• 900535-75-3 tert-butyl 4-(1-hydroxypropan-2-yl)piperazine-1-carboxylate 

Relevant articles and documents

DERIVATIVES OF N-[(1H-PYRAZOL-1-YL)ARYL]-1H-INDOLE OR 1H-INDAZOLE-3-CARBOXAMIDE, PREPARATION THEREOF AND APPLICATIONS THEREOF IN THERAPEUTICS

The present invention relates to compounds corresponding to formula (I): in which: A represents a divalent aromatic radical; X represents a —CH— group or a nitrogen atom; R1 represents a (C1-C4)alkyl or a (C1-C4)alkoxy; R2 represents a group Alk; R3 represents a hydroxyl or a group —NR7R8; R4 represents a hydrogen atom, a halogen atom, a cyano, a phenyl, a group Alk, a group OAlk or a group —NR9R10; R5 represents a hydrogen atom, a halogen atom or a group Alk; R6 represents a hydrogen atom, a halogen atom, a cyano, a group —COOAlk or a —CONH2 group.

DERIVATIVES OF N- [(1H-PYRAZOL-1-YL) ARYL] - 1H - INDOLE OR 1H - INDAZOLE - 3 - CARBOXAMIDE, THEIR PREPARATION AND THEIR USE AS P2Y12 ANTAGONISTS

The present invention relates to compounds corresponding to formula (I) and their use as P2Y12 antagonists for the treatment of cardiovascular diseases.