- Pyridone-containing polycyclic derivative inhibitor as well as preparation method and application thereof
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The invention relates to a pyridone-containing polycyclic derivative inhibitor as well as a preparation method and an application thereof. In particular, the present invention relates to a compound represented by general formula (I), a preparation method
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Paragraph 0322; 0325-0327
(2021/05/12)
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- OXAZOLIDONE COMPOUND, PREPARING METHOD AND APPLICATION THEREOF
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The present invention relates to the field of a pharmaceutical compound, and more specifically, relates to a new oxazolidone compound, an enantiomer, a diastereoisomer and a raceme thereof, and a mixture thereof, and a pharmaceutically acceptable salt thereof, a preparation method thereof, an application thereof as a bioactive substance in a drug. The compound in the present invention has strong anticoagulant activity, does not affect the activity of thrombin, and can reduce the risk of hemorrhage. A pharmacokinetics experiment shows that the compound in the present invention further has good metabolic characteristics, and has a far better oral bioavailability than a positive contrastive agent rivaroxaban.
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Paragraph 0089; 0090; 0091
(2015/12/08)
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