681484-77-5

Basic information

• Product Name: Piperazine, 2-[(1S)-1-methylpropyl]-, (2S)-
• Synonyms: (S)-2-((S)-SEC-BUTYL)-PIPERAZINE;(2S)-2-[(2S)-butan-2-yl]piperazine;Piperazine, 2-[(1S)-1-methylpropyl]-, (2S)-
• CAS NO: 681484-77-5
• Molecular Formula: C8H18N2
• Molecular Weight: 142.2419
• Mol File: 681484-77-5.mol

Chemical Properties

• Boiling Point: 201.018°C at 760 mmHg
• Flash Point: 76.285°C
• Appearance: /
• Density: 0.851g/cm³
• Vapor Pressure: 0.315mmHg at 25°C
• Refractive Index: 1.435
• Storage Temp.: 2-8°C
• PKA: 9.31±0.40(Predicted)
• CAS DataBase Reference: Piperazine, 2-[(1S)-1-methylpropyl]-, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 2-[(1S)-1-methylpropyl]-, (2S)-(681484-77-5)
• EPA Substance Registry System: Piperazine, 2-[(1S)-1-methylpropyl]-, (2S)-(681484-77-5)

Safety Data

• Hazardous Substances Data: 681484-77-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Piperazine, 2-[(1S)-1-methylpropyl]-, (2S)is used as a key intermediate in the synthesis of various drugs due to its diverse pharmacological properties. Its anthelmintic, antiviral, and antipsychotic activities make it a valuable compound for the development of new medications.
Used in Medical Research and Development:
Piperazine, 2-[(1S)-1-methylpropyl]-, (2S)has potential applications in medical research and development, where its unique properties can be further explored and utilized to create innovative therapeutic solutions for various health conditions.

InChI:InChI=1/C8H18N2/c1-3-7(2)8-6-9-4-5-10-8/h7-10H,3-6H2,1-2H3/t7-,8+/m0/s1

Upstream product

• 324749-84-0 (3S)-1-(benzyl)-3-(1-methylpropyl)piperazine 
• 677021-17-9 3-sec-butylpiperazine-2,5-dione 

Relevant articles and documents

CYANOGUANIDINES AND THEIR USE AS ANTIVIRAL AGENTS

This disclosure relates to: (a) compounds and salts thereof that, inter alia, inhibit RSV infection and/or replication; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.

Piperazine derivative

A piperazine compound represented by formula (1): wherein X is —CH2—, —C(O)— or —CH(CH3)—; R1is a hydrogen atom or alkyl group; and R2is a hydrogen atom, alkyl group, hydroxyalkyl group, arylalkyl group, heteroarylalkyl group, carboxyalkyl group, carboxamidoalkyl group, aminoalkyl group or guanidinoalkyl group; an acid-addition salt thereof, or a hydrate thereof. The compound has excellent inhibitory effects on both cell adhesion and cell infiltration and is useful for prevention or treatment of diseases such as allergy, asthma, rheumatism, arteriosclerosis and inflammation.