681508-73-6 Usage
Classification
Piperazine derivative
Function
Serotonin receptor antagonist
Research use
Tool compound to study serotonin receptor function
Potential therapeutic uses
a. Depression
b. Anxiety
c. Psychosis
Investigated for
Managing drug addiction and withdrawal symptoms
Affinity
Moderate affinity for dopamine receptors
Suggested applications
Treatment of Parkinson's disease and other dopamine-related disorders
Research status
Further research needed to understand pharmacological properties and potential therapeutic uses
Check Digit Verification of cas no
The CAS Registry Mumber 681508-73-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,8,1,5,0 and 8 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 681508-73:
(8*6)+(7*8)+(6*1)+(5*5)+(4*0)+(3*8)+(2*7)+(1*3)=176
176 % 10 = 6
So 681508-73-6 is a valid CAS Registry Number.
681508-73-6Relevant articles and documents
Novel CXCR3 antagonists with a piperazinyl-piperidine core
McGuinness, Brian F.,Carroll, Carolyn DiIanni,Zawacki, Lisa Guise,Dong, Guizhen,Yang, Cangming,Hobbs, Doug W.,Jacob-Samuel, Biji,Hall III, James W.,Jenh, Chung-Her,Kozlowski, Joseph A.,Anilkumar, Gopinadhan N.,Rosenblum, Stuart B.
scheme or table, p. 5205 - 5208 (2010/03/31)
High-throughput screening of an encoded combinatorial aryl piperazine library led to the identification of a novel series of potent piperazinyl-piperidine based CXCR3 antagonists. Analogs of the initial hit were synthesized via solid and solution phase me