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681847-93-8

1-Piperidinepropanamine,2-methyl-,(2R)-(9CI) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 681847-93-8 Structure

  • Basic information

    1. Product Name: 1-Piperidinepropanamine,2-methyl-,(2R)-(9CI)
    2. Synonyms: 1-Piperidinepropanamine,2-methyl-,(2R)-(9CI);(R)-3-(2-methylpiperidin-1-yl)propan-1-amine
    3. CAS NO:681847-93-8
    4. Molecular Formula: C9H20N2
    5. Molecular Weight: 156.27
    6. EINECS: N/A
    7. Product Categories: AMINETERTIARY
    8. Mol File: 681847-93-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-Piperidinepropanamine,2-methyl-,(2R)-(9CI)(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-Piperidinepropanamine,2-methyl-,(2R)-(9CI)(681847-93-8)
    11. EPA Substance Registry System: 1-Piperidinepropanamine,2-methyl-,(2R)-(9CI)(681847-93-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 681847-93-8(Hazardous Substances Data)

681847-93-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 681847-93-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,8,1,8,4 and 7 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 681847-93:
(8*6)+(7*8)+(6*1)+(5*8)+(4*4)+(3*7)+(2*9)+(1*3)=208
208 % 10 = 8
So 681847-93-8 is a valid CAS Registry Number.

681847-93-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-Piperidinepropanamine,2-methyl-,(2R)-(9CI)

1.2 Other means of identification

Product number -
Other names 2-Heptadecanol,1-[(2-hydroxyethyl)methylamino]-,(R)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:681847-93-8 SDS

681847-93-8Relevant articles and documents

Noncyclam tetraamines inhibit CXC chemokine receptor type 4 and target glioma-initiating cells

Ros-Blanco, Laia,Teixido, Jordi,Borrell, Jose I.,Anido, Judit,Seoane, Joan,Bosser, Ramon,Kosoy, Ana,Ruiz-Avila, Luis,Este, Jose,Clotet, Bonaventura

, p. 7560 - 7570,11 (2020/08/24)

The three stereoisomers of the noncyclam compound 1 (1(R,R), 1(S,S), and the meso form 1(S,R)) and their corresponding tetrahydrochlorides 11 were prepared from (S)- and (R)-2-methylpiperidine. We have evaluated their inhibitory activity on the CXC chemokine receptor type 4 (CXCR4), toxicity properties, and assessment of their effect on glioma initiating cells (GICs) in comparison with the prototype compound AMD3100. The IC50 values determined on human recombinant (CHO) cells showed very similar inhibitory activities albeit a lower KB for AMD3100, with the 1(R,R) isomer being second in potency. All the compounds showed low cardiac toxicity but, contrary to AMD3100, gave maximum nonlethal doses of around 2.0 mg/kg. The CXCR4 inhibitors had an effect on the state of differentiation of GICs, decreasing the percentage of CD44+ cells in glioblastoma multiform neurospheres in vitro. Moreover, these CXCR4 inhibitors blocked the capacity of cells to initiate orthotopic tumors in immunocompromised mice.

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