Aliphatic ethers and esters of 1-(2,4-dichlorophenyl)-2-(1H-imidazolyl)ethanol: study of antifungal activity against yeasts and hydrophobic character
Aliphate ethers 2 and esters 3, which are closely related to antifungal azoles, were synthesized and tested against various strains of Candida.We found that their activity was strongly related to the length of the chains; the best activity was obtained wi
Wahbi, Y.,Tournaire, C.,Caujolle, R.,Payard, M.,Linas, M. D.,Seguela, J. P.
p. 701 - 706
(2007/10/02)
1-Phenethylimidazoles
Novel 1-phenethylimidazoles substituted at the position β to the imidazole ring by an optionally substituted hydrocarbyl ester, thioester, or dithioester are useful as antimicrobial agents and as intermediates in the preparation of novel 1-phenethylimidazoles substituted at the position β to the imidazole with a mercapto. Both the former and latter compounds are useful as intermediates in the preparation of certain 1-[β-(R-thio)phenethyl] imidazoles.
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(2008/06/13)
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