689294-25-5Relevant articles and documents
SOLID FORMS OF CEFTOLOZANE AND PROCESSES FOR PREPARING
-
Sheet 7, (2018/01/17)
The instant invention is related to a novel solid form of ceftolozane sulfate (the DMAc solvate of ceftolozane sulfate (Form 3)), compositions comprising ceftolozane sulfate DMAc solvate (Form 3), synthesis of Form 3 and an improved crystallization proces
INTERMEDIATES IN THE SYNTHESIS OF CEPHALOSPORIN COMPOUNDS
-
Sheet 3, (2016/02/29)
Described herein are crystalline forms of a compound of formula (ΙΙΓ), including toluene solvates ofT A TD-CLE, as well as processes for the preparation thereof and use thereof in the preparation of cephalosporin compounds such as ceftolozane. Provided he
Synthesis and SAR of novel parenteral anti-pseudomonal cephalosporins: Discovery of FR264205
Toda, Ayako,Ohki, Hidenori,Yamanaka, Toshio,Murano, Kenji,Okuda, Shinya,Kawabata, Kohji,Hatano, Kazuo,Matsuda, Keiji,Misumi, Keiji,Itoh, Kenji,Satoh, Kenji,Inoue, Satoshi
scheme or table, p. 4849 - 4852 (2009/05/07)
We describe herein the synthesis and biological evaluation of a series of novel cephalosporins with potent activity against Pseudomonas aeruginosa. Introduction of various amino groups to the 4-position of a 3-amino-2-methylpyrazole cephalosporin 3-side c
CEPHEM COMPOUNDS
-
Page/Page column 34, (2010/02/11)
The present invention relates to a compound of the formula [I]: wherein R1 is lower alkyl or hydroxy (lower) alkyl, and R2 is hydrogen or amino protecting group, or R1 and R2 are bonded together and form lower a
CEPHEM COMPOUNDS
-
Page 68 - 69, (2010/02/06)
The present invention relates to a compound of the formula [I]: wherein R1 is lower alkyl, hydroxy(lower)alkyl or halo(lower)alkyl, and R2 is hydrogen or amino protecting group, or R1 and R2 are bonded together and form lower alkylene or lower alkenylene; R3 is hydrogen or lower alkyl; R4 is ; R5 is carboxy or protected carboxy; and R6 is amino or protected amino, or a pharmaceutically acceptable salt thereof, a process for preparing a compound of the formula [I], and a pharmaceutical composition comprising a compound of the formula [I] in admixture with a pharmaceutically acceptable carrier.