Synthesis and structure/NMDA receptor affinity relationships of 1-substituted tetrahydro-3-benzazepines
A novel synthesis of 1-substituted tetrahydro-1H-3-benzazepines 4 is described. Starting with (2-bromophenyl)acetaldehyde acetal 5, the nitrostyrene 9 was prepared in three steps allowing the addition of various nucleophiles to yield the nitroacetals 10.
Krull, Olaf,Wuensch, Bernhard
p. 1439 - 1451
(2007/10/03)
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