Synthesis and radiopharmacological study of unsaturated derivatives of cysteamine
Synthesis of many unsaturated compounds derivated from cysteamine has been carried out in the three series : β-aminothioethers, β-aminothiols and thiazolidines. These products are more or less toxic, compared to corresponding saturated derivates. They generally have a higher radioprotective activity. The three most effective have a dose reduction factor equivalent to that of cysteamine, two of them having a lower toxicity.