Synthesis and fungicidal activity of 5-aryl-1-(aryloxyacetyl)-3-(tert-butyl or phenyl)-4-(1h-1,2,4-triazol-1-yl)-4,5-dihydropyrazole
A series of novel 5-aryl-1-(aryloxyacetyl)-3-(tert-butyl or phenyl)-4-(1H-1,2,4-triazol-1-yl)-4,5-dihydropyrazole - were synthesized by the annulation of 2-aryloxyacetohydrazides with 3-aryl-1-t-butyl (or phenyl)-2-(1H-1,2,4-triazol-1-yl)prop-2-en-1-ones
Mao, Hui-Yu,Song, Hong,Shi, De-Qing
p. 216 - 219
(2013/06/05)
New lead compounds for brassinosteroid biosynthesis inhibitors
The first brassinosteroid biosynthesis inhibitor is reported. Among newly synthesized triazole derivatives, 4-(4-chlorophenyl)-2-phenyl-3- (1,2,4-triazoyl)butan-2-ol (6) was found to inhibit the growth of cress seedlings, and this inhibition was recovered by the treatment of brassinolide, suggesting that compound 6 primarily inhibits brassinosteroid biosynthesis.