N-Monomethylation of Primary Amines via Intermediate Benzothiazol-2(3H)-imines
Aliphatic and aromatic amines are converted by successive treatment with (i) 3-methyl-2-methylthiobenzothiazolium iodide, (ii) methyl iodide or toluene-p-sulphonate, and (iii) butylamine, in high yield under mild conditions into their mono-N-methyl derivatives.
Katritzky, Alan R.,Drewniak, Malgorzata,Aurrecoechea, Jose M.
p. 2539 - 2542
(2007/10/02)
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