Self-assembly of aliphatic dipeptides coupled with porphyrin and BODIPY chromophores
In this work, the self assembly ability of chromophores covalently linked to aliphatic dipeptides is described. Altering various parameters such as the protecting group, the solvent mixture, the dipeptide and the chromophore resulted in different nanostru
Nikoloudakis, Emmanouil,Mitropoulou, Konstantina,Landrou, Georgios,Charalambidis, Georgios,Nikolaou, Vasilis,Mitraki, Anna,Coutsolelos, Athanassios G.
An efficient synthetic method of N-protected dipeptide acids using amino acid calcium carboxylates in an organic solvent
The syntheses of N-protected dipeptide acids using alkaline earth metal (Mg, Ca, and Ba) carboxylates of an amino acid in organic solvents were investigated. It was found that amino acid calcium carboxylates are the most effective among the carboxylates of the amino acids tested for coupling with active esters of Boc-Ala-OH in organic solvents. The coupling of Boc-Ala-ONp or Boc-Ala-ONSu with amino acid calcium carboxylates in DMF gave the desired N-protected dipeptide acids in high yields (92-100%). Georg Thieme Verlag Stuttgart - New York.