Welcome to LookChem.com Sign In|Join Free

CAS

  • or

70458-73-0

PEFLOXACIN IMPURITY B is a chemical compound derived from the quinolone class of antibiotics, specifically from the synthesis process of pefloxacin. It is characterized by its chemical structure, which includes a quinoline core with a carboxylic acid group and various substituents that contribute to its properties and potential applications.

70458-73-0 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 70458-73-0 Structure

  • Basic information

    1. Product Name: PEFLOXACIN IMPURITY B
    2. Synonyms: PEFLOXACIN IMPURITY B;1-Ethyl-6-chloro-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid;Pefloxacin Impurity 1
    3. CAS NO:70458-73-0
    4. Molecular Formula: C17H20ClN3O3
    5. Molecular Weight: 349.81
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 70458-73-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: PEFLOXACIN IMPURITY B(CAS DataBase Reference)
    10. NIST Chemistry Reference: PEFLOXACIN IMPURITY B(70458-73-0)
    11. EPA Substance Registry System: PEFLOXACIN IMPURITY B(70458-73-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 70458-73-0(Hazardous Substances Data)

70458-73-0 Usage

Uses

Used in Pharmaceutical Industry:
PEFLOXACIN IMPURITY B is used as an intermediate in the synthesis of therapeutic diphosphonates for the pharmaceutical industry. These diphosphonates are compounds that have applications in the treatment of various bone-related disorders, such as osteoporosis and Paget's disease, due to their ability to inhibit bone resorption and promote bone formation.
Additionally, PEFLOXACIN IMPURITY B may have potential applications in the development of new antibiotics or other therapeutic agents, given its structural similarities to known bioactive compounds. Further research and development would be required to explore these possibilities and determine the compound's suitability for such uses.

Check Digit Verification of cas no

The CAS Registry Mumber 70458-73-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,4,5 and 8 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 70458-73:
(7*7)+(6*0)+(5*4)+(4*5)+(3*8)+(2*7)+(1*3)=130
130 % 10 = 0
So 70458-73-0 is a valid CAS Registry Number.

70458-73-0 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail

  • Sigma-Aldrich

  • (P0309020)  Pefloxacin impurity B  European Pharmacopoeia (EP) Reference Standard

  • 70458-73-0

  • P0309020

  • 1,880.19CNY

  • Detail

70458-73-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-ethyl-6-chloro-7-(4-methyl-1-piperazinyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid

1.2 Other means of identification

Product number -
Other names 6-chloro-1-ethyl-7-(4-methylpiperazinyl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:70458-73-0 SDS

70458-73-0Downstream Products

70458-73-0Relevant articles and documents

Substituted quinoline carboxylic acid derivatives

-

, (2008/06/13)

This invention relates to new compounds of value as antibacterial agents. More particularly, it relates to quinoline carboxylic acid derivatives, the hydrates and the acid or alkali addition salts thereof.

Structure-Activity Relationships of Antibacterial 6,7- and 7,8-Disubstituted 1-Alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic Acids

Koga, Hiroshi,Itoh, Akira,Murayama, Satoshi,Suzue, Seigo,Irikura, Tsutomu

, p. 1358 - 1363 (2007/10/02)

Previous quantitative and qualitative structure-activity studies in antibacterial monosubstituted 1-ethyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids prompted us to synthesize the 6,7,8-polysubstituted compounds.In this paper, the preparation and antibacterial activity of the 6,7- and 7,8-disubstituted compounds and their derivatives are described.Among these compounds, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)quinoline-3-carboxylic acid (34) possessed many significant activities and was more active than oxolinic acid (84) against Gram-positive andGram-negative bacteria.Structure activity relationships are discussed.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 70458-73-0