705291-51-6Relevant articles and documents
First functionalization by metallation of the pyridine moiety of pyridopyrimidin-4(3H)-ones. Diazines. Part 36
Audoux, Jér?me,Plé, Nelly,Turck, Alain,Quéguiner, Guy
, p. 4107 - 4123 (2007/10/03)
Starting from o-aminopyridine carboxylic acids, a general synthetic route leading to various pyridopyrimidin-4(3H)-ones is described. The first metallation and functionalization of the pyridine moiety has been studied and a regioselective metallation at the peri-position C5 of the pyridine ring has been highlighted.