705944-49-6

Basic information

• Product Name: 2H-1-Benzopyran-2-one, 8-fluoro-7-hydroxy-
• Synonyms: 2H-1-Benzopyran-2-one, 8-fluoro-7-hydroxy-
• CAS NO: 705944-49-6
• Molecular Formula: C9H5FO3
• Molecular Weight: 0
• Mol File: 705944-49-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2H-1-Benzopyran-2-one, 8-fluoro-7-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran-2-one, 8-fluoro-7-hydroxy-(705944-49-6)
• EPA Substance Registry System: 2H-1-Benzopyran-2-one, 8-fluoro-7-hydroxy-(705944-49-6)

Safety Data

• Hazardous Substances Data: 705944-49-6(Hazardous Substances Data)

Upstream product

• 93-35-6 7-hydroxy-2H-chromen-2-one 

Relevant articles and documents

Synthesis and anti-inflammatory activity of natural and semisynthetic geranyloxycoumarins

Nine new 7-geranyloxycoumarin derivatives differently substituted at position 8 were semi-synthesised. Their topical anti-inflammatory activity was evaluated using the Croton oil ear test in mice as a model of acute inflammation. Auraptene (7-geranyloxycoumarin), its 8-methoxy (collinin, 1) and 8-acetoxy derivatives (5) (1μmol/cm2) provoked 50% oedema reduction, similarly to 0.25μmol/cm2 of the reference drug indomethacin, a nonsteroidal anti-inflammatory drug.