Epimerization of 2- or 4- substituted cyclohexanecarboxylic acids
The present invention relates to a new method for obtaining a purity of about 93% to 100% of the trans form of 2- or 4-substituted cyclohexanecarboxylic acid or reactive derivatives thereof from the cis form or a mixture of the cis and trans forms by a single step, particularly, to a method for obtaining a purity of substantially 100% of the trans form of 4-substituted cyclohexanecarboxylic acid.
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(2008/06/13)
Preparation and anticancer activity of 2-diethylaminoethyl-cis- and -trans-methylcyclohexanecarboxylates.
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Harmon,Meulman,Gupta
p. 871 - 872
(2007/10/06)
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