cas 70862-11-2, thermospermine | Articles data ｜lookchem

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70862-11-2

Articles about 70862-11-2Total 3 be found

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Practical synthesis of spermine, thermospermine and norspermine
Polyamines, such as spermine (1), thermospermine (2) and norspermine (3), are widely distributed in nature, and have multiple biological activities. In addition, many of their conjugates have potential for pharmacological use. Here, we present a solid-phase synthesis using our nitrobenzenesulfonyl (Ns) strategy, which can provide 1, 2 and 3 on a gram scale. This approach should be suitable for facile construction of a diverse library of polyamines.
Kariya, Yuka,Asanuma, Yuta,Inai, Makoto,Asakawa, Tomohiro,Ohashi-Ito, Kyoko,Fukuda, Hiroo,Egi, Masahiro,Kan, Toshiyuki
p. 1403 - 1407
(2016/09/09)

The chemistry of naturally occurring polyamines. A total synthesis of thermospermine
{A figure is presented} methodology for distinguishing the similar basic sites in spermidine has led to the first synthesis of thermospermine 1.
Chantrapromma, Kan,McManis, James S.,Ganem, Bruce
p. 2475 - 2476
(2007/10/02)

Substrate binding characteristics of the active site of spermidine dehydrogenase from Serratia marcescens
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Okada,Kawashima,Imahori
p. 1235 - 1243
(2007/10/05)

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Chemical Properties

Boiling Point: 330.9°C at 760 mmHg
Flash Point:180.3°C
Density: 0.925g/cm³
Vapor Pressure: 0.000161mmHg at 25°C
PKA: 10.48±0.10(Predicted)
PSA: 76.10000
LogP: 1.82580

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