- AMINOAMIDE COMPOUNDS
-
Compounds with amino amide linkers and pharmaceutical compositions and medicaments comprising such compounds are disclosed. The compounds modulate protein function of 1L-1β, IL-2, IL-6, TNF-α, CK1α, GSPT1, aiolos, ikaros or helios, or combinations thereof. In addition, methods of making such compounds and their uses for treating or ameliorating diseases, disorders, or conditions associated with protein malfunction, such as cancer, are provided.
- -
-
-
- Squarylium compound
-
PROBLEM TO BE SOLVED: To provide a squarylium compound excellent in stability in a polar solvent, a solution containing the same and a resin composition. SOLUTION: There is provided a squarylium compound represented by the following formula (1), where Rs
- -
-
Paragraph 0097; 0098
(2018/08/30)
-
- Substituted benzazoles and methods of their use as inhibitors of Raf kinase
-
New substituted benz-azole compounds, compositions and methods of inhibition of Raf kinase activity in a human or animal subject are provided. The new compounds compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
- -
-
-