Design and synthesis of malonic acid-based inhibitors of human neutrophil collagenase (MMP8)
For most of the known synthetic inhibitors of matrix metalloproteinases (MMPs), a substrate-like binding mode was postulated on the basis of X-ray crystallographic structures of MMP/ inhibitor complexes. Conversely, the malonic acid-based inhibitor (2R, S
Von Reedern, Erich Graf,Grams, Frank,Brandstetter, Hans,Moroder, Luis
p. 339 - 345
(2007/10/03)
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