- Ring Transformation of 3-Hydroxy-1,2,5- and -1,2,4-thiadiazoles and -isothiazoles into Isothiazole , Thiazole and Thiophene Derivatives
-
Ring transformation of 3-hydroxy-1,2,5-thiadiazole (1), 3-hydroxy-1,2,4-thiadiazole (14), and 3-hydroxyisothiazole (18) by the reaction with acetic anhydride in the presence of DBU afforded isothiazoles 2-5 and 13, thiazoles 15 and 16 and thiophenes 21-25, respectively.The reaction of 1 with propionic anhydride gave isothiazole 13.The formation pathway of the products is mentioned.
- Mataka, Shuntaro,Takahashi, Kazufumi,Tashiro, Masashi
-
p. 1496 - 1502
(2007/10/02)
-
- Pharmaceutical compositions containing 4-amido-thiazoles
-
The invention relates to pharmaceutical compositions for use in treating ulcers or hypersecretion comprising a compound of formula I STR1 wherein R is hydrogen, alkyl of 1 to 6 carbon atoms, or COR3 where R3 is hydrogen, alkyl of 1 t
- -
-
-