A new approach to the synthesis of 4-(N-aryl)carbamoylmethyl-4,5- dihydropyridazin-3(2H)-ones
Reaction of N-aryl substituted maleimides with aliphatic ketazines leads to the formation of 4,5-dihydropyridazin-3(2H)-ones in moderate yields. The reaction proceeds through 1,4-addition of an azine to the maleimide double bond, as confirmed by separatio
Stepakov, Alexander V.,Kinzhalov, Michail A.,Boitsov, Vitaly M.,Stepakova, Liubov V.,Starova, Galina L.,Vyazmin, Sergey Yu.,Grinenko, Elena V.
experimental part
p. 3146 - 3149
(2011/06/28)
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