724788-29-8

Basic information

• Product Name: Carbamic acid, [(3R,4R)-3-hydroxy-4-piperidinyl]-, 1,1-dimethylethyl ester (9CI)
• Synonyms: Carbamic acid, [(3R,4R)-3-hydroxy-4-piperidinyl]-, 1,1-dimethylethyl ester (9CI);CarbaMic acid, [(3R,4R)-3-hydroxy-4-piperidinyl]-, 1,1-diMethylethyl ester;(3R,4R)-(3-Hydroxy-piperidin-4-yl)-carbamic acid tert-butyl ester;tert-butyl N-[(3R,4R)-3-hydroxypiperidin-4-yl]carbamate;(3R,4R)-4-(BOC-AMINO)-3-HYDROXYPIPERIDINE
• CAS NO: 724788-29-8
• Molecular Formula: C10H20N2O3
• Molecular Weight: 216.2774
• Product Categories: N-BOC
• Mol File: 724788-29-8.mol

Chemical Properties

• Boiling Point: 363.4±42.0 °C(Predicted)
• Appearance: /
• Density: 1.11±0.1 g/cm3(Predicted)
• PKA: 11.88±0.40(Predicted)
• CAS DataBase Reference: Carbamic acid, [(3R,4R)-3-hydroxy-4-piperidinyl]-, 1,1-dimethylethyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, [(3R,4R)-3-hydroxy-4-piperidinyl]-, 1,1-dimethylethyl ester (9CI)(724788-29-8)
• EPA Substance Registry System: Carbamic acid, [(3R,4R)-3-hydroxy-4-piperidinyl]-, 1,1-dimethylethyl ester (9CI)(724788-29-8)

Safety Data

• Hazardous Substances Data: 724788-29-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
Carbamic acid, [(3R,4R)-3-hydroxy-4-piperidinyl]-, 1,1-dimethylethyl ester (9CI) is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure, including the piperidinyl group and hydroxy functional group, allows for the development of new drugs with potential therapeutic applications.
Used in Drug Reagent Preparation:
Carbamic acid, [(3R,4R)-3-hydroxy-4-piperidinyl]-, 1,1-dimethylethyl ester (9CI) serves as a reagent for the preparation of different drugs, contributing to the advancement of pharmaceutical research and development. Its versatility in chemical reactions and potential biological activities make it a valuable asset in the creation of novel drug candidates.
Used in Biological Research:
Carbamic acid, [(3R,4R)-3-hydroxy-4-piperidinyl]-, 1,1-dimethylethyl ester (9CI) is utilized in biological research to study its potential biological activities and explore its applications in various therapeutic areas. Its unique structure and functional groups enable researchers to investigate its interactions with biological targets and evaluate its efficacy in addressing specific health conditions.
Used in Chemical Synthesis:
In the field of chemical synthesis, this compound is employed as a building block for the creation of complex organic molecules. Its reactivity and functional groups make it suitable for various synthetic routes, allowing chemists to develop new compounds with diverse applications in different industries.
Used in Drug Delivery Systems:
Carbamic acid, [(3R,4R)-3-hydroxy-4-piperidinyl]-, 1,1-dimethylethyl ester (9CI) can be incorporated into drug delivery systems to improve the bioavailability and therapeutic outcomes of various drugs. Its unique structure and functional groups can be exploited to design novel drug carriers, enhancing the delivery of pharmaceutical compounds to their target sites.

Relevant articles and documents

Novel amino-piperidines as potent antibacterials targeting bacterial type IIA topoisomerases

We have identified a series of amino-piperidine antibacterials with a good broad spectrum potency. We report the investigation of various subunits in this series and advanced studies on compound 8. Compound 8 possesses good pharmacokinetics, broad spectrum antibacterial activity and demonstrates oral efficacy in a rat lung infection model.

ANTIBACTERIAL AGENTS

Naphthalene, quinoline, quinoxaline and naphthyridine derivatives useful in the treatment of bacterial infections in mammals, particularly humans, are disclosed herein.