Spirocyclopropane compounds. III. Synthesis of spiro[benzofuran-2(3H),1'-cyclopropan]-3-ones for evaluation of gastric antisecretory and antiulcer agents
Spiro[benzofuran-2(3H),1'-cyclopropan]-3-one (VI-1) and its derivatives (VI-2 - VI-75) were synthesized in the same manner as described previously for the synthesis of spiro[cyclopropane-1,2'-[2H]indol]-3'(1'H)-ones (I). These spiro[benzofuran-2(3H),1'-cy