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2-Hydroxy-5-thioureido-benzoic acid, also known as Thiouracil, is a chemical compound with potential pharmaceutical applications. It belongs to the class of organic compounds known as benzoic acids and derivatives. It is a derivative of uracil and contains a thiourea functional group, which gives it unique biological properties. Its ability to inhibit thyroid hormone synthesis and regulate cell growth makes it a promising candidate for the development of new therapeutic agents.
Used in Pharmaceutical Industry:
2-Hydroxy-5-thioureido-benzoic acid is used as a pharmaceutical agent for its potential use in the treatment of various medical conditions, including hyperthyroidism and cancer. Its unique biological properties, such as the ability to inhibit thyroid hormone synthesis and regulate cell growth, make it a promising candidate for the development of new therapeutic agents.
Used in Thyroid Hormone Regulation:
2-Hydroxy-5-thioureido-benzoic acid is used as a thyroid hormone regulator for its potential to inhibit thyroid hormone synthesis. This property makes it a candidate for the treatment of hyperthyroidism, a condition characterized by an overactive thyroid gland.
Used in Cancer Treatment:
2-Hydroxy-5-thioureido-benzoic acid is used as a potential cancer treatment agent due to its ability to regulate cell growth. This property suggests that it may be effective in treating various types of cancer, although further research is needed to fully understand and harness its potential in this area.

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  • 728918-63-6 Structure
  • Basic information

    1. Product Name: 2-HYDROXY-5-THIOUREIDO-BENZOIC ACID
    2. Synonyms: 2-HYDROXY-5-THIOUREIDO-BENZOIC ACID
    3. CAS NO:728918-63-6
    4. Molecular Formula: C8H8N2O3S
    5. Molecular Weight: 212.23
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 728918-63-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-HYDROXY-5-THIOUREIDO-BENZOIC ACID(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-HYDROXY-5-THIOUREIDO-BENZOIC ACID(728918-63-6)
    11. EPA Substance Registry System: 2-HYDROXY-5-THIOUREIDO-BENZOIC ACID(728918-63-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 728918-63-6(Hazardous Substances Data)

728918-63-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 728918-63-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,2,8,9,1 and 8 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 728918-63:
(8*7)+(7*2)+(6*8)+(5*9)+(4*1)+(3*8)+(2*6)+(1*3)=206
206 % 10 = 6
So 728918-63-6 is a valid CAS Registry Number.

728918-63-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-HYDROXY-5-THIOUREIDO-BENZOIC ACID

1.2 Other means of identification

Product number -
Other names 2-Hydroxy-5-tert-pentyl-benzoesaeure

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:728918-63-6 SDS

728918-63-6Downstream Products

728918-63-6Relevant articles and documents

Identification of a novel selective small-molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) by virtual screening, resynthesis and biological evaluations

Zhu, Kongkai,Jiang, Chengshi,Tao, Hongrui,Liu, Jingqiu,Zhang, Hua,Luo, Cheng

supporting information, p. 1476 - 1483 (2018/04/20)

As one of the most promising anticancer target in protein arginine methyltransferase (PRMT) family, PRMT5 has been drawing more and more attentions, and many efforts have been devoted to develop its inhibitors. In this study, three PRMT5 inhibitors (9, 16

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