728919-15-1

Basic information

• Product Name: 4'-TRIFLUOROMETHOXY-BIPHENYL-2-YLAMINE
• Synonyms: 4'-TRIFLUOROMETHOXY-BIPHENYL-2-YLAMINE;4'-(Trifluoromethoxy)-biphenyl-2-amine
• CAS NO: 728919-15-1
• Molecular Formula: C₁₃H₁₀F₃NO
• Molecular Weight: 253.22
• Mol File: 728919-15-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4'-TRIFLUOROMETHOXY-BIPHENYL-2-YLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-TRIFLUOROMETHOXY-BIPHENYL-2-YLAMINE(728919-15-1)
• EPA Substance Registry System: 4'-TRIFLUOROMETHOXY-BIPHENYL-2-YLAMINE(728919-15-1)

Safety Data

• Hazardous Substances Data: 728919-15-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4'-Trifluoromethoxy-biphenyl-2-ylamine is used as a building block for the synthesis of complex molecules with potential biological activities. Its unique chemical structure, including the trifluoromethoxy group, contributes to the development of new drugs with enhanced lipophilicity and biological potency.
Used in Agrochemical Industry:
In the agrochemical sector, 4'-Trifluoromethoxy-biphenyl-2-ylamine serves as a key component in the creation of novel agrochemicals. Its chemical properties allow for the development of effective compounds with improved performance in agricultural applications.
Used in Material Science:
4'-Trifluoromethoxy-biphenyl-2-ylamine is utilized in the development of new materials, capitalizing on its chemical properties to engineer innovative substances with a range of applications in various industries.

Upstream product

• 615-43-0 2-iodophenylamine 
• 139301-27-2 4-trifluoromethoxyphenylboronic acid 

Downstream Products

• 1019997-48-8 2-[4-(tert-butyl)phenyl]amino-4'-(trifluoromethoxy)biphenyl 

Relevant articles and documents

Modular Tandem Mizoroki-Heck/Reductive Heck Reactions to Construct Fluorenes from Cyclic Diaryliodoniums

Starting from cyclic diaryliodoniums and terminal alkenes, a diverse set of fluorenes is conveniently constructed. The reactions catalyzed by palladium undergo one conventional Mizoroki-Heck reaction and one reductive Heck reaction. The scope of alkenes is general, leading to 29 fluorenes which would expand the structural diversity of fluorene reservoir. (Figure presented.).

Radical Fluoroalkylation of Isocyanides with Fluorinated Sulfones by Visible-Light Photoredox Catalysis

The radical fluoroalkylation of isocyanides with fluorinated sulfones is enabled by visible-light photoredox catalysis. A wide range of readily available mono-, di-, and trifluoromethyl heteroaryl sulfones can thus be used as efficient radical fluoroalkylation reagents under mild conditions. This method not only describes a new synthetic application of fluorinated sulfones, but also provides a new route to fluoroalkyl radicals.

N-Phenyloxamide derivatives

A compound represented by the following general formula (I) or a salt thereof, or a hydrate thereof or a solvate thereof having an inhibitory action against plasminogen activator inhibitor-1 (PAI-1): wherein R1 represents a C6-10 aryl group; or a C6-10 aryl group substituted with a group or groups selected from the group consisting of a halogen atom, cyano group, nitro group, a C1-6 alkyl group, a halogenated C1-6 alkyl group, a C1-6 alkoxy group, a halogenated C1-6 alkoxy group and a C1-6 alkylsulfanyl group, R2 represents a C6-10 aryl group; or a C6-10 aryl group substituted with a group or groups selected from the group consisting of a halogen atom, hydroxy group, a C1-6 alkyl group, a halogenated C1-6 alkyl group, a C1-6 alkoxy group, a halogenated C1-6 alkoxy group, a C1-6 alkylsulfanyl group and phenyl group, X represents a single bond or oxygen atom, Z represents a phenylene group or a substituted phenylene group, m represents 0 or 1.