- Hepatitis C Virus Inhibitors
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The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.
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- COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS
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The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit the function of the NS5A protein encoded by Hepatitis C virus (HCV), compositions comprising such combinations, and methods for inhibiting the function of the NS5A protein.
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- Combating fungi with substituted triazolylalkyl pyridyl ethers
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Substituted triazolylalkyl pyridyl ethers of the formula STR1 in which R1 is a halogen atom, R2 is a hydrogen or halogen atom, X is a keto group or a CH(OH) group, Y each independently is a halogen atom or an alkyl, alkoxy or cyano group, and n is 0, 1, 2, 3 or 4, or an addition product thereof with a physiologically acceptable acid or metal salt which possesses fungicidal activity. Intermediates therefor wherein X is a keto group and with a halogen atom in place of either the pyridinyloxy group or the azole group are also new.
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- Combating fungi with acylated imidazolyl-gamma-fluoropinacolyl derivatives
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Fungicidally active acylated imidazolyl-γ-fluoropiniacolyl derivatives of the formula STR1 in which R represents alkyl, alkenyl, alkynyl, alkoxy, alkoxyalkyl, cycloalkyl, halogenoalkyl, optionally substituted phenyl, optionally substituted phenylalkyl, op
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- Combating fungi with 1-phenoxy -1-imidazol-1-yl-4-fluoro-butane derivatives
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1-Phenoxy-1-imidazol-1-yl-4-fluoro-butane derivatives of the formula STR1 in which B is --CO- or --CH(OH)--, X is hydrogen or fluorine, Z each independently is halogen, alkyl, nitro, cyano, alkoxy-carbonyl or optionally substituted phenyl, and n is 0, 1,
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- Combating fungi with 1-phenoxy-1-triazolyl-3-fluoromethyl-butane derivatives
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1-Phenoxy-1-triazolyl-3-fluoromethyl-butane derivatives of the formula STR1 in which Az is 1,2,4-triazol-1-yl or 1,2,4-triazol-4-yl, B is --CO-- or --CH(OH)--, X is hydrogen or fluorine, Z each independently is halogen, alkyl, nitro, cyano, alkoxy-carbony
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- Combating arthropods with substituted 2-carbamoyloximino-butanes
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Substituted 2-carbamoyloximino-butanes of the formula STR1 in which R is alkyl or alkylthioalkyl, R1 is alkyl, alkoxyalkyl, alkenyl or alkynyl, R2 is hydrogen, alkyl or --SR3, R3 is alkyl, halogenoalkyl, optionally substituted phenyl, alkoxycarbonyl, --N(CH3)R4, or a radical identical to that to which --SR3 is bonded, R4 is alkyl, alkoxycarbonyl or optionally substituted phenylsulphonyl, X is hydrogen or halogen, Y is hydrogen or halogen, Z is halogen, and n is 0, 1 or 2, which possess arthropodicidal activity.
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- Acylated triazolyl-γ-fluoropinacolyl derivatives and their use as fungicides
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Fungicidally active acylated triazolyl-γ-fluoropinacolyl derivatives of the formula STR1 in which Az represents 1,2,4-triazol-1-yl or 1,2,4-triazol-4-yl, R represents alkyl, alkenyl, alkynyl, alkoxy, alkoxyalkyl, cycloalkyl, halogenoalkyl, optionally subs
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- Preparation of side-chain fluorinated 3,3-dimethyl-butan-2-one
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A fluorine derivative of 3,3-dimethyl-butan-2-one, of the formula STR1 in which X is hydrogen or fluorine, is produced by reacting a metal fluoride in a diluent and at elevated temperature with a sulphonic acid ester of the formula STR2 in which R is opti
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