731859-02-2 Usage
Uses
Used in Pharmaceutical Research and Development:
(R)-6-Fluoro-2,3-dihydro-1H-inden-1-amine hydrochloride is used as a chiral building block for the synthesis of various pharmaceutical compounds. Its unique stereochemistry allows for selective interactions with biological targets, making it a valuable component in the development of new drugs.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (R)-6-Fluoro-2,3-dihydro-1H-inden-1-amine hydrochloride is used as a precursor for the development of drugs targeting serotonin and dopamine receptors in the central nervous system. Its specific configuration enables it to modulate these receptors, potentially leading to the treatment of neurological and psychiatric disorders.
Used in Drug Synthesis:
(R)-6-Fluoro-2,3-dihydro-1H-inden-1-amine hydrochloride serves as a key intermediate in the synthesis of various drug molecules. Its presence in the molecular structure can influence the drug's pharmacokinetic and pharmacodynamic properties, such as absorption, distribution, metabolism, and excretion, as well as its efficacy and safety profiles.
Used in Chiral Drug Development:
As a chiral compound, (R)-6-Fluoro-2,3-dihydro-1H-inden-1-amine hydrochloride is used in the development of enantiomerically pure drugs. The "R" configuration allows for the creation of drugs with specific biological activities, reducing potential side effects and improving therapeutic outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 731859-02-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,3,1,8,5 and 9 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 731859-02:
(8*7)+(7*3)+(6*1)+(5*8)+(4*5)+(3*9)+(2*0)+(1*2)=172
172 % 10 = 2
So 731859-02-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H10FN.ClH/c10-7-3-1-6-2-4-9(11)8(6)5-7;/h1,3,5,9H,2,4,11H2;1H/t9-;/m1./s1
731859-02-2Relevant articles and documents
Identification of N-acyl-N-indanyl-α-phenylglycinamides as selective TRPM8 antagonists designed to mitigate the risk of adverse effects
Kobayashi, Jun-ichi,Hirasawa, Hideaki,Fujimori, Yoshikazu,Nakanishi, Osamu,Kamada, Noboru,Ikeda, Tetsuya,Yamamoto, Akitoshi,Kanbe, Hiroki
, (2020/12/21)
Transient receptor potential melastatin 8 (TRPM8), a temperature-sensitive ion channel responsible for detecting cold, is an attractive molecular target for the treatment of pain and other disorders. We have previously discovered a selective TRPM8 antagon
Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators
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Page 31, (2008/06/13)
Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators. The invention relates to an optically active compound of formula (I) or a salt thereof: wherein the various symbols are as defined in the description, to proceses for their preparation, to compositions thereof, and to their use as herbicides or plant growth regulators. The invention also relates to novel intermediates of formula (III), (V) and (XIII) as defined in the description.
