732976-86-2

Basic information

• Product Name: 3-Azetidinecarbonitrile
• Synonyms: 3-Azetidinecarbonitrile;3-Azetidinecarboniteile
• CAS NO: 732976-86-2
• Molecular Formula: C₄H₆N₂
• Molecular Weight: 82.10384
• Mol File: 732976-86-2.mol

Chemical Properties

• Boiling Point: 193.6±33.0 °C(Predicted)
• Appearance: /
• Density: 1.05±0.1 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Sealed in dry,Store in freezer, under -20°C
• PKA: 8.25±0.40(Predicted)
• CAS DataBase Reference: 3-Azetidinecarbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Azetidinecarbonitrile(732976-86-2)
• EPA Substance Registry System: 3-Azetidinecarbonitrile(732976-86-2)

Safety Data

• Hazardous Substances Data: 732976-86-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Azetidinecarbonitrile is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to form complex molecular structures that can target specific biological pathways. Its incorporation into drug molecules can enhance their efficacy and selectivity, leading to improved treatments for a range of diseases and conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Azetidinecarbonitrile serves as a vital component in the development of new pesticides and herbicides. Its unique chemical properties allow for the creation of compounds that can effectively control pests and weeds while minimizing environmental impact.
Used in Organic Synthesis:
3-Azetidinecarbonitrile is utilized as a versatile building block in organic synthesis, enabling the construction of a wide array of chemical compounds with diverse applications. Its reactivity and structural flexibility make it an ideal candidate for the synthesis of complex organic molecules.
Used in Chemical Research and Development:
3-Azetidinecarbonitrile is employed as a precursor in the production of other important chemicals, contributing to the advancement of new materials and compounds. Its unique properties and potential applications make it a valuable resource in the ongoing research and development efforts across various chemical industries.

Upstream product

• 142253-54-1 tert-butyl 3-cyanoazetidine-1-carboxylate 

Downstream Products

• 1246495-11-3 1-(1-methyl-1H-imidazol-4-ylsulfonyl)azetidine-3-carbonitrile 
• 1258065-54-1 (R)-1-(2-(6-chloro-3-oxopyrrolo[4,3,2-de][2,6]naphthyridin-4(1H,3H,5H)-yl)-3-methylbutanoyl)azetidine-3-carbonitrile 
• 1239361-85-3 (S)-N²-[1-(4-fluorophenyl)ethyl]-6-(3-methoxysalicylicazetidin-1-yl)-N⁴-(aminopyrazine-2-yl)-2,4-diamine 
• 1415969-22-0 [(R)-1-(3-cyano-azetidine-1-carbonyl)-2,2-dimethyl-propyl]-carbamic acid tert-butyl ester 
• 1426136-44-8 6-bromo-N-(5-(5-((3-cyanoazetidin-1-yl)methyl)-1,2,4-oxadiazol-3-yl)-2-methylphenyl)imidazo[1,2-a]pyridine-3-carboxamide 

Relevant articles and documents

Therapeutic agent pcnsl (by machine translation)

The present invention provides a malignant lymphoma therapeutic or preventive agent that comprises as the active ingredient a compound represented by general formula [1] as defined by (I) or (II), or a pharmaceutically acceptable salt thereof. [1] (I) X is CH or N; R1 is a halogen; R2 is a halogen, H, a cyano, a group represented by general formula [9], [9] an optionally substituted heteroaryl, or the like; R3 is H or a hydroxyl; R4 is H or an alkyl; and R5 is H or an alkyl. (II) X is -CRA, RA is -CORB, RB is an optionally substituted amino, alkoxy, or saturated cyclic amino group; R1 is a halogen; R2 is H; R3is H or a hydroxy; R4 is H or an alkyl; and R5 is H or an alkyl.

SULFONYL-AZETIDIN-3-YL-METHYLAMINE AMIDE ANALOGS AS GLYT1 INHIBITORS, METHODS FOR MAKING SAME, AND USE OF SAME IN TREATING PSYCHIATRIC DISORDERS

In one aspect, the invention relates to compounds which are useful as as inhibitors of glycine type 1 transporter (GIyT1) activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with glycine type 1 transporter (GIyT1) activity using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.