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CAS

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736930-12-4

N-(2-bromo-4,5-dimethoxybenzyl)-5-quinolinamine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 736930-12-4 Structure

  • Basic information

    1. Product Name: N-(2-bromo-4,5-dimethoxybenzyl)-5-quinolinamine
    2. Synonyms:
    3. CAS NO:736930-12-4
    4. Molecular Formula:
    5. Molecular Weight: 373.249
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 736930-12-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: N-(2-bromo-4,5-dimethoxybenzyl)-5-quinolinamine(CAS DataBase Reference)
    10. NIST Chemistry Reference: N-(2-bromo-4,5-dimethoxybenzyl)-5-quinolinamine(736930-12-4)
    11. EPA Substance Registry System: N-(2-bromo-4,5-dimethoxybenzyl)-5-quinolinamine(736930-12-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 736930-12-4(Hazardous Substances Data)

736930-12-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 736930-12-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,3,6,9,3 and 0 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 736930-12:
(8*7)+(7*3)+(6*6)+(5*9)+(4*3)+(3*0)+(2*1)+(1*2)=174
174 % 10 = 4
So 736930-12-4 is a valid CAS Registry Number.

736930-12-4Downstream Products

736930-12-4Relevant articles and documents

Synthesis and cytotoxic activity of benzo[c][1,7] and [1,8]phenanthrolines analogues of nitidine and fagaronine

Prado, Soizic,Michel, Sylvie,Tillequin, Francois,Koch, Michel,Pfeiffer, Bruno,Pierre, Alain,Leonce, Stephane,Colson, Pierre,Baldeyrou, Brigitte,Lansiaux, Amelie,Bailly, Christian

, p. 3943 - 3953 (2004)

Fagaronine and nitidine are natural benzo[c] phenanthridinium alkaloids, which display antileukemic activity. Both act as topoisomerase I and topoisomerase II inhibitors. The objective of the present study was to prepare noncharged isosters of these compounds, with replacement of the aromatic A ring by a pyridine ring, present in other topoisomerase I inhibitors. Various 7,8- and 8,9-dimethoxy and metylenedioxy benzo[c][1,7] and [1,8]phenanthrolines were readily synthesized by benzyne-mediated cyclization of the corresponding substituted N-(2-halobenzyl)-5-quinolinamines or 5-isoquinolinamines. In both series, compounds bearing oxygenated substituents at positions 8 and 9 exhibited cytotoxic properties towards L1210 murine leukemia cells, which may result from their capacities to intercalate into DNA. Topoisomerase I inhibition was observed for all active compounds.

Synthesis and biological evaluation of dialkylaminoalkylamino benzo[c][1,7] and [1,8]phenanthrolines as antiproliferative agents

?erbet?i, Tuba,Genès, Constance,Depauw, Sabine,Prado, Soizic,Porée, Fran?ois-Hugues,Hildebrand, Marie-Paule,David-Cordonnier, Marie-Hélène,Michel, Sylvie,Tillequin, Fran?ois

scheme or table, p. 2547 - 2558 (2010/07/09)

Benzo[c][1,7] and [1,8]phenanthroline substituted by dialkylaminoalkyl side chains at position C2 and C1, respectively, were synthesized and their biological activity evaluated. These compounds displayed more potent cytotoxicity toward L1210 cells than th

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