737001-01-3Relevant articles and documents
Electrochemical Benzylic C(sp3)-H Isothiocyanation
Guo, Weisi,Li, Ming,Li, Yufeng,Wang, Tao,Wen, Lirong,Zhang, Shanxue
supporting information, p. 1742 - 1746 (2022/03/14)
Selective C(sp3)-H isothiocyanation represents a significant strategy for the synthesis of isothiocyanate derivatives. We report herein an electrochemical benzylic isothiocyanation in a highly chemo- and site-selective manner under external oxidant-free conditions. The high chemoselectivity is attributed to the facile in situ isomerization of benzylic thiocyanates to isothiocyanates. Notably, the method exhibits high functional group compatibility and is suitable for late-stage functionalization of bioactive molecules.
Selectfluor F-TEDA-BF4 mediated thiocyanation or isothiocyanation of alcohols by in situ generation of [+SCN] under heterogeneous and neutral conditions
Khazaei, Ardeshir,Rahmati, Sadegh,Khalafi-Nezhad, Ali,Saednia, Shahnaz
experimental part, p. 123 - 125 (2012/05/05)
A convenient approach for thiocyanation of alcohols has been developed using ammonium thiocyanate as thiocyanating agent in the presence of a catalytic amount of Selectfluor F-TEDA-BF4 in aqueous acetonitrile. In this method various alcohols generally afforded the corresponding thiocyanates or isothiocyanates directly in good to high yield under heterogeneous and neutral conditions.
Synthesis and antitumor activity of optically active thiourea and their 2-aminobenzothiazole derivatives: A novel class of anticancer agents
Manjula,Malleshappa Noolvi,Vipan Parihar,Manohara Reddy,Ramani, Vijay,Gadad, Andanappa K.,Singh, Gurdial,Gopalan Kutty,Mallikarjuna Rao
experimental part, p. 2923 - 2929 (2009/09/30)
A novel series of optically active 2-aminobenzothiazole derivatives were synthesized by reaction of optically active amine (I) with thiophosgene to obtain optically active isothiocyanates (IIa-h) which on condensation with 4-fluoro-3-chloro aniline (III)
