737801-80-8

Basic information

• Product Name: N-(1H-INDOL-7-YL)-2-PHENOXYACETAMIDE
• Synonyms: N-(1H-INDOL-7-YL)-2-PHENOXYACETAMIDE
• CAS NO: 737801-80-8
• Molecular Formula: C₁₆H₁₄N₂O₂
• Molecular Weight: 266.29
• Mol File: 737801-80-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(1H-INDOL-7-YL)-2-PHENOXYACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1H-INDOL-7-YL)-2-PHENOXYACETAMIDE(737801-80-8)
• EPA Substance Registry System: N-(1H-INDOL-7-YL)-2-PHENOXYACETAMIDE(737801-80-8)

Safety Data

• Hazardous Substances Data: 737801-80-8(Hazardous Substances Data)

Upstream product

• 5192-04-1 7-aminoindole 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 1315307-87-9 ethyl (7-benzyloxycarbonylamino-1H-indol-3-yl)glyoxylate 
• 1315307-76-6 6-benzyloxycarbonylamino-2,5-dihydro-2-phenyl-4H-pyrazolo[3,4-c]quinolin-4-one 
• 1315307-93-7 C₂₃H₁₇N₅ 
• 1315307-83-5 6-benzylamino-2-phenyl-2H-pyrazolo[3,4-c]quinolin-4-amine 
• 1315307-92-6 2-phenyl-2H-pyrazolo[3,4-c]quinolin-4,6-diamine 
• 1315307-91-5 6-benzyloxycarbonylamino-2-phenyl-2H-pyrazolo[3,4-c]quinolin-4-amine 
• 1315307-90-4 6-benzyloxycarbonylamino-4-chloro-2-phenyl-2H-pyrazolo[3,4-c]quinoline 
• 1315307-78-8 6-amino-2,5-dihydro-2-phenyl-4H-pyrazolo[3,4-c]quinolin-4-one 

Relevant articles and documents

(S)-N-{3-[1-cyclopropyl-1-(2,4-difluoro-phenyl)-ethyl]-1H-indol-7-yl} -methanesulfonamide: A potent, nonsteroidal, functional antagonist of the mineralocorticoid receptor

A novel, potent series of indole analogs were recently developed as MR antagonists, culminating in 14. This compound represents the first MR antagonist in this class of molecules, exhibiting picomolar binding affinity and in vivo blood pressure lowering at pharmaceutically relevant doses.

BICYCLIC SUBSTITUTED INDOLE-DERIVATIVE STEROID HORMONE NUCLEAR RECEPTOR MODULATORS

The present invention provides a compound of the formula: Formula (I); or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising an effective amount of a compound of Formula I in combination with a suitable carrier, diluent, or excipient, and methods for treating physiological disorders, particularly congestive heart disease, hypertension, and atherosclerosis, comprising administering to a patient in thereof an effective amount of a compound of Formula I. X-16125

INDOLE-DERIVATIVE MODULATORS OF STEROID HORMONE NUCLEAR RECEPTORS

The present invention provides a compound of formula I or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising an effective amount of a compound of Formula I in combination with a suitable carrier, diluent, or excipient, and methods for treating physiological disorders, particularly congestive heart disease, comprising administering to a patient in thereof an effective amount of a compound of Formula I.