Catalytic activity of a zirconium(IV) Schiff base complex in facile and highly efficient synthesis of indole derivatives
Eight Schiff base compounds were prepared by condensation of 1-amino-2-propanol with different benzaldehydes in water. One of the Schiff bases, (z)-N-bezylidene-2-hydroxypropane-1-amine (HL1), was used as a bidentate ligand for preparation of a
Design, synthesis, and structure-activity relationship exploration of 1-substituted 4-aroyl-3-hydroxy-5-phenyl-1 H -pyrrol-2(5 H)-one analogues as inhibitors of the annexin A2′S100A10 protein interaction
S100 proteins are small adaptors that regulate the activity of partner proteins by virtue of direct protein interactions. Here, we describe the first small molecule blockers of the interaction between S100A10 and annexin A2. Molecular docking yielded cand
Reddy, Tummala R. K.,Li, Chan,Guo, Xiaoxia,Myrvang, Helene K.,Fischer, Peter M.,Dekker, Lodewijk V.
experimental part
p. 2080 - 2094
(2011/05/30)
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