739365-93-6

Basic information

• Product Name: (S)-TERT-BUTYL 4-CARBAMOYLTHIAZOLIDINE-3-CARBOXYLATE
• Synonyms: (S)-TERT-BUTYL 4-CARBAMOYLTHIAZOLIDINE-3-CARBOXYLATE
• CAS NO: 739365-93-6
• Molecular Formula: C9H16N2O3S
• Molecular Weight: 0
• Mol File: 739365-93-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-TERT-BUTYL 4-CARBAMOYLTHIAZOLIDINE-3-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-TERT-BUTYL 4-CARBAMOYLTHIAZOLIDINE-3-CARBOXYLATE(739365-93-6)
• EPA Substance Registry System: (S)-TERT-BUTYL 4-CARBAMOYLTHIAZOLIDINE-3-CARBOXYLATE(739365-93-6)

Safety Data

• Hazardous Substances Data: 739365-93-6(Hazardous Substances Data)

Upstream product

• 63091-82-7 (S)-3-(tert-butoxycarbonyl)thiazolidine-4-carboxylic acid 

Downstream Products

• 884006-57-9 (4S)-N-boc-1,3-thiazolane-4-carbonitrile 

Relevant articles and documents

NEW ADAMANTANE DERIVATIVES AS DIPEPTIDYL, PEPTIDASE IV INHIBITORS, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

The present invention relates to dipeptidyl peptidase IV (DPP-IV) inhibitors of the formula (A): wherein R1, R2, Y, and n are as defined herein, pharmaceutical compositions containing the same, processes for their preparation, and methods for treating disorders mediated by DPP-IV inhibition, such as diabetes, especially Type II diabetes, with them.

NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION

The present invention relates to novel compounds useful as dipeptidyl peptidase IV (DPP-IV) inhibitors of the formula: (I) wherein Y is -S(O)m, -CH2-, CHF, or -CF2; m is 0, 1, or 2; X is a bond, C1-C5 alkyl (e.g., -CH2-), or -C(=0)-; the dotted line [----] in the carbocyclic ring represents an optional double bond; R1 is substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkylalkyl, substituted or unsubstituted cycloalkenyl, substituted or unsubstituted aryl, substituted or unsubstituted arylalkyl, substituted or unsubstituted heteroaryl, substituted or unsubstituted heterocyclic ring, substituted or unsubstituted heterocyclylalkyl, substituted or unsubstituted heteroarylalkyl, CN, -COOR3, CONR3R4, -OR3, -NR3R4, or NR3COR3; R2 is hydrogen, cyano, COOH, or an isostere of a carboxylic acid (such as SO3H, CONOH, B(OH)2, PO3R3R4, SO2NR3R4, tetrazole, -COOR3, -CONR3R4, NR3COR4, or -COOCOR3).

NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS; PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS THEREOF

The present invention relates to novel dipeptidyl peptidase IV (DPP-IV) inhibitors or general formula (1) useful for treating diabetes, non-insulin dependent diabetes mellitus, impaired glucose tolerance, inflammatory bowel disease, ulcerative colitis,Chron’s disease, obesity, and metabolic syndrome.