Triazolopyrimidines. V. The Nucleophilic Substitution of 7-Chloro- and 7-(p-Tolylsulfonyl)-3-phenyl-3H-1,2,3-triazolopyrimidines
The substitution reaction of 7-chloro- (1) and 7-(p-tolylsulfonyl)-3-phenyl-3H-1,2,3-triazolopyrimidines (2) with various nucleophiles (NuH or Nu(-)) was carried out.The reaction of 1 with amines (NuH-1 to NuH-11) gave 7-(N-substituted amino)-3-phe
Triazolopyrimidines. VI. 3-Phenyl-3H-1,2,3-triazolopyrimidine-7-carbonitrile and Related Compounds
Nucleophilic reagents were found to react with 3-phenyl-3H-1,2,3-triazolopyrimidine-7-carbonitrile (1) in two ways, depending on the nature of the reagent.One is substitution by attack of the reagent on the carbon at the 7-position, to which the cy