745833-19-6

Basic information

• Product Name: Ethyl 2-(2,4-difluorophenyl)-6-chloronicotinate
• Synonyms: ETHYL 2-(2,4-DIFLUOROPHENYL)-6-CHLORONICOTINATE;6-Chloro-2-(2,4-difluoro-phenyl)nicotinic acid ethyl ester;6-Chloro-2-(2,4-difluorophenyl)-3-pyridinecarboxylic acid ethyl ester;5-Chloro-2-(2,4-difluoro-phenyl)-nicotinic acid ethyl ester;3-Pyridinecarboxylic acid, 6-chloro-2-(2,4-difluorophenyl)-, ethyl ester
• CAS NO: 745833-19-6
• Molecular Formula: C14H10ClF2NO2
• Molecular Weight: 297.68
• Product Categories: Heterocyclic Compounds
• Mol File: 745833-19-6.mol

Chemical Properties

• Boiling Point: 371.4 °C at 760 mmHg
• Flash Point: 178.4 °C
• Appearance: /
• Density: 1.336 g/cm³
• Refractive Index: 1.543
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Ethyl 2-(2,4-difluorophenyl)-6-chloronicotinate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 2-(2,4-difluorophenyl)-6-chloronicotinate(745833-19-6)
• EPA Substance Registry System: Ethyl 2-(2,4-difluorophenyl)-6-chloronicotinate(745833-19-6)

Safety Data

• Hazardous Substances Data: 745833-19-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Ethyl 2-(2,4-difluorophenyl)-6-chloronicotinate is used as an intermediate in the synthesis of various pharmaceutical drugs. Its unique chemical structure and properties contribute to the development of new and effective medications.
Used in Drug Discovery and Development:
Ethyl 2-(2,4-difluorophenyl)-6-chloronicotinate is used as a key component in drug discovery and development due to its potential therapeutic applications and significant biological activities. It aids in the identification and optimization of new drug candidates.
Used in Chemical Research:
Ethyl 2-(2,4-difluorophenyl)-6-chloronicotinate is used in chemical research for its unique chemical and physical properties. It serves as a versatile compound for exploring various research applications and advancing the understanding of fluoro substituted pyridine derivatives.

InChI:InChI=1/C14H10ClF2NO2/c1-2-20-14(19)10-5-6-12(15)18-13(10)9-4-3-8(16)7-11(9)17/h3-7H,2H2,1H3

Upstream product

• 1219503-90-8 2-(2,4-difluorophenyl)-3-(ethoxycarbonyl)pyridine 1-oxide 

Relevant articles and documents

SOLID FORMS OF 2-(2, 4-DIFLUOROPHENYL)-6-(1-(2,6-DIFLUOROPHENYL)UREIDO)NICOTINAMIDE

This invention relates to solid forms of 2-(2, 4-difluorophenyl)-6-(l- (2,6-difluorophenyl)ureido)nicotinamide and pharmaceutical compositions thereof, and methods and uses therewith.

PROCESSES FOR PRODUCING PHENYL-6-(1-(PHENYL)UREIDO)NICOTINAMIDES)

The present invention relates to processes for the preparation of compounds useful as inhibitors of p38 kinase. The processes of the present invention are amenable for large scale preparation and produce stable phenyl-6-(l-(phenyl)ureido)nicotinamides in