Lignans of Guaiacum officinale L.: Photo-sensitized Aerial Oxidation of 2,5-Diaryl-3,4-dimethylfurans and a Novel Method of Sequential Introduction of Alkoxy Functions in Their 3-and 4-Methyl Groups
From the polar extractives of 'lignum vitae', the heartwood of Guaiacum officinale, were isolated two new lignans, designated furoguaiacidin and furoguaiaoxidin, as their respective diethyl ether derivatives 1a and 2a. The structures of these lignans were
Majumder,Chakrabarty, Manju
p. 776 - 783
(2007/10/03)
A novel synthetic route to furan-lignans
Three naturally occurring furan-lignans and two analogs have been synthesized by a short and efficient route starting from the corresponding aryl acid. The selective reductive removal of allylic hydroxy by palladium oxide in a mixed solvent of THF-CHCl3 was employed as the key step.