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749200-87-1

3-(5-Piperidin-4-yl-[1,3,4]oxadiazol-2-yl)-pyridine is a heterocyclic chemical compound with a molecular formula C12H13N5O. It features a pyridine ring, an oxadiazole ring, and a piperidine moiety, which contribute to its potential pharmacological properties. 3-(5-Piperidin-4-yl-[1,3,4]oxadiazol-2-yl)-pyridine is of interest in medicinal chemistry for the development of new drugs due to its unique structure and possible biological activity.

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  • 749200-87-1 Structure

  • Basic information

    1. Product Name: 3-(5-Piperidin-4-yl-[1,3,4]oxadiazol-2-yl)-pyridine
    2. Synonyms: 3-(5-Piperidin-4-yl-[1,3,4]oxadiazol-2-yl)-pyridine;2-(piperidin-4-yl)-5-(pyridin-3-yl)-1,3,4-oxadiazole;Pyridine, 3-[5-(4-piperidinyl)-1,3,4-oxadiazol-2-yl]-;4-[5-(3-pyridinyl)(1,3,4-oxadiazol-2-yl)]piperidine
    3. CAS NO:749200-87-1
    4. Molecular Formula: C12H14N4O
    5. Molecular Weight: 230
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 749200-87-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-(5-Piperidin-4-yl-[1,3,4]oxadiazol-2-yl)-pyridine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-(5-Piperidin-4-yl-[1,3,4]oxadiazol-2-yl)-pyridine(749200-87-1)
    11. EPA Substance Registry System: 3-(5-Piperidin-4-yl-[1,3,4]oxadiazol-2-yl)-pyridine(749200-87-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 749200-87-1(Hazardous Substances Data)

749200-87-1 Usage

Uses

Used in Medicinal Chemistry:
3-(5-Piperidin-4-yl-[1,3,4]oxadiazol-2-yl)-pyridine is used as a compound in medicinal chemistry for the development of new drugs. Its structure suggests potential effects on the central nervous system, as well as possible anti-inflammatory and antimicrobial properties, making it a promising candidate for further research and development.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 3-(5-Piperidin-4-yl-[1,3,4]oxadiazol-2-yl)-pyridine is used as a subject for research to explore its potential applications in drug development. Its unique structure and the presence of heterocyclic rings indicate that it may possess biological activity that could be harnessed for therapeutic purposes.
Used in Drug Development:
3-(5-Piperidin-4-yl-[1,3,4]oxadiazol-2-yl)-pyridine is used in drug development as a starting point for designing new pharmaceuticals. Its potential pharmacological properties and the possibility of modifying its structure to enhance its activity make it a valuable asset in the search for novel therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 749200-87-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,4,9,2,0 and 0 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 749200-87:
(8*7)+(7*4)+(6*9)+(5*2)+(4*0)+(3*0)+(2*8)+(1*7)=171
171 % 10 = 1
So 749200-87-1 is a valid CAS Registry Number.

749200-87-1Downstream Products

749200-87-1Relevant articles and documents

Triazole alcohol antifungal compound with piperidine oxadiazole side chain and preparation method for compound and application of compound

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Paragraph 0110; 0111, (2016/10/07)

The invention relates to the medical technical field and provides 1-(1H-1,2,4-triazole-1-yl)-2-(2,4-difluorophenyl)-3-(piperidine oxadiazole side chain substituted)-2-propanol compounds in one category. The compound comprises cis-trans-isomers thereof and any mixtures in the forms or pharmaceutical salts thereof. The chemical structural formula of the compound is represented by a formula (I). The invention further provides a preparation method for the compound and an application of the compound in preparing antifungal drugs. From an antifungal experiment, the compound provided by the invention has a very strong antifungal effect on various superficial fungi and deep fungi. Compared with existing clinically applied antifungal drugs such as fluconazole, the compound has the advantages of being efficient, low in toxicity and wide in antifungal spectrum, has relatively good activity on fluconazole drug-resistant bacteria and can be used for preparing antifungal drugs. The formula is shown in the description.

Discovery of highly potent triazole antifungal agents with piperidine-oxadiazole side chains

He, Xiaomeng,Jiang, Yan,Zhang, Yongqiang,Wu, Shanchao,Dong, Guoqiang,Liu, Na,Liu, Yang,Yao, Jianzhong,Miao, Zhenyuan,Wang, Yan,Zhang, Wannian,Sheng, Chunquan

, p. 653 - 664 (2015/04/27)

Due to increasing incidence and mortality of invasive fungal infections, discovery and development of new generations of antifungal agents represents a challenging task. On the basis of our previously reported triazole-benzyloxypiperidinyl lead compound, a series of novel triazole antifungal agents containing piperidine-oxadiazole side chains were rationally designed and synthesized. Most of the target compounds showed excellent inhibitory activity against clinically important fungal pathogens. In particular, compounds 6g (MIC = 0.031 μg mL-1) and 11b (MIC = 0.016 μg mL-1) were highly active against Candida albicans including fluconazole-resistant strains. Moreover, they showed inhibitory activity against hyphal formation with low toxicity, which were promising leads for further development. This journal is

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