74924-97-3

Basic information

• Product Name: 2-hydroxy-3-oxo-trans-decalin
• CAS NO: 74924-97-3
• Molecular Weight: 156.225
• Mol File: 74924-97-3.mol

Chemical Properties

• CAS DataBase Reference: 2-hydroxy-3-oxo-trans-decalin(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-3-oxo-trans-decalin(74924-97-3)
• EPA Substance Registry System: 2-hydroxy-3-oxo-trans-decalin(74924-97-3)

Safety Data

• Hazardous Substances Data: 74924-97-3(Hazardous Substances Data)

Upstream product

• 74925-00-1 (3R,4aR,8aS)-3-Methoxy-octahydro-isochromene 
• 74924-99-5 2-oxa-3α-methoxy-cis-decalin 
• 18335-58-5 trans-2,3-tetramethylene-δ-valerolactone 

Relevant articles and documents

Models for Glycoside Hydrolysis. Synthesis and Hydrolytic Studies of the Anomers of a Conformationally Rigid Acetal

The methyl acetals of 2-hydroxy-3-oxa-trans-decalin were synthesized as models for conformationally rigid methyl glycosides.The compounds were prepared by Baeyer-Villiger oxidation of trans-hexahydrohydrindan-2-one followed by reduction of the resulting lactone with diisobutylaluminum hydride.Treatment of the hemiacetal with methanol and an acid catalyst afforded a mixture of acetals which were separated by chromatography and identified by NMR.Hydrolytic studies were carried out under a range of acid concentrations and temperatures.The mechanistic implications of the relative hydrolysis rates (axial/equatorial ratio of 1.51+/-0.22) and activation parameters are discussed.