Diuretic Agents Related to Indapamide. 1. Synthesis and Activity of 1-Substituted 2-(4-Chloro-3-sulfamoylbenzamido)isoindolines
The synthesis of isoindoline analogues of indapamide is described.These substances (4a,c,d) were tested for diuretic activity, and 4a was found to be comparable in potency to indapamide.
Cignarella, Giorgio,Sanna, Paolo,Miele, Egidio,Anania, Vittorio,Desole, Maria S.
p. 1003 - 1006
(2007/10/02)
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