- Compound TVA-X having neuroprotection effect, preparation method and applications thereof
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The invention relates to a compound TVA-X having neuroprotection effect, a preparation method and applications thereof, and provides a class of compounds having a structure general formula 1, and a preparation method thereof, and applications in preparation of drugs for treatment of brain nerve injury and sequela thereof, wherein the composition can significantly protect cobalt chloride induced PC12 cell damage, wherein the compound VA-06 has strong protection effect on cobalt chloride induced PC12 cell damage compared to the positive drug ligustrazine. The formula 1 is defined in the specification.
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- The Reaction of Alkylpyrazine Anions with Some Electrophiles. Synthesis of 1,2-bis(2-pyrazyl)ethanes
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The reaction of alkylpyrazine anions with iodine, 1,2-dibromoethylene or oxygen gives 1,2-bis(2-pyrazyl)ethanes.
- Houminer, Yoram,Sanders, Edward B.
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p. 647 - 649
(2007/10/02)
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