76049-51-9

Basic information

• Product Name: 2-CHLORO-2'-IODOBENZOPHENONE
• Synonyms: 2-CHLORO-2'-IODOBENZOPHENONE
• CAS NO: 76049-51-9
• Molecular Formula: C₁₃H₈ClIO
• Molecular Weight: 342.56
• Mol File: 76049-51-9.mol

Chemical Properties

• Boiling Point: 422.6°C at 760 mmHg
• Flash Point: 209.4°C
• Appearance: /
• Density: 1.699g/cm³
• Vapor Pressure: 2.38E-07mmHg at 25°C
• Refractive Index: 1.653
• CAS DataBase Reference: 2-CHLORO-2'-IODOBENZOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-2'-IODOBENZOPHENONE(76049-51-9)
• EPA Substance Registry System: 2-CHLORO-2'-IODOBENZOPHENONE(76049-51-9)

Safety Data

• Hazardous Substances Data: 76049-51-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H8ClIO/c14-11-7-3-1-5-9(11)13(16)10-6-2-4-8-12(10)15/h1-8H

Upstream product

• 2894-45-3 (2-aminophenyl)(2-chlorophenyl)methanone 

Downstream Products

• 76049-55-3 1-[2-(2-chlorobenzoyl)phenyl]-3-phthalimidopropyne 

Relevant articles and documents

TRIAZOLE DERIVATIVES AS TACHYKININ RECEPTOR ANTAGONISTS

This application relates to a compound of Formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions thereof, and its use as an inhibitor of the NK-1 subtype of tachykinin receptors, as well as a process for its preparation and intermediates therefor. (I) wherein: D is a C1-C3 alkane-diyl; R1 is phenyl, which is optionally substituted with one to three substitutents indpendently selected from the group consisting of halo, C1-C4 alkyl, C1-C4 alkoxy, cyano, difluoromethyl, trifluoromethyl, and trifluoromethoxy; R4 is a radical selected from the group consisting of: (IA), (IB), (IC), (ID), (IE), (IF), (IG), (IH)

3H-2-Benzazepines

There is presented 3H-2-benzazepines and 4,5-dihydro-3H-2-benzazepines of the formula STR1 wherein X is hydrogen, chloro or bromo, Y is hydrogen, fluoro or chloro with the proviso that X and Y cannot both be hydrogen and R1 is selected from the

N-oxides of 5-oxo-1-phenyl-2-benzazepines

Compounds of the formula STR1 wherein X and Y are selected from the group consisting of hydrogen, halogen and trifluoromethyl, are disclosed. The compounds are useful as intermediates in the production of 2-benzazepines, compounds of pharmacological activ

2-Benzazepines. 1. Synthesis of 2-Benzazepin-4-ones and -5-ones via 2-Acetylenic Benzophenones

The preparation of 1-phenyl-2-benzazepin-4-ones and -5-ones is discussed.The palladium-catalyzed coupling of an iodobenzophenone to a monosubstituted acetylene assembles the necessary atoms required for the benzazepine ring.Transformation of the acetylene

Intermediates in the production of 2-benzazepines

Compounds of the formula STR1 wherein X and Y are selected from the group consisting of hydrogen, halogen and trifluoromethyl, are disclosed. The compounds are useful as intermediates in the production of 2-benzazepines, compounds of pharmacological activ

Triazolobenzazepines and processes for their production

There is presented triazolobenzazepines of the formula STR1 wherein R1 is hydrogen or lower alkyl and X and Y are hydrogen or halogen and the pharmaceutically acceptable salts thereof. Also disclosed are novel processes and intermediates leadin