TOTAL SYNTHESIS OF (+/-)-AVENACIOLIDE AND ITS ANALOGUES
A new method for the stereoselective synthesis of (+/-)-avenaciolide and its analogues via methoxycarbonyl- or anisyloxycarbonyldi-γ-lactones, which could be easily prepared by the reaction of γ-substituted α-bromobutenolides with sodium salt of methyl or anisyl malonamate in good yields, was described.