765306-76-1Relevant articles and documents
Arynes in a three-component coupling reaction: Straightforward synthesis of benzoannulated iminofurans
Yoshida, Hiroto,Fukushima, Hiroyuki,Ohshita, Joji,Kunai, Atsutaka
, p. 3935 - 3938 (2004)
Mix the components, stir, and ... voila! A variety of benzoannulated iminofurans can be obtained in this straightforward manner from an aryne, an isocyanide, and an aldehyde in modest to high yields (see scheme). Perfect regioselectivity was observed with a 3-substituted aryne and 4-fluorobenzyne, whereas 4-methylbenzyne gave a mixture of regioisomers.
Three-component coupling using arynes and isocyanides: straightforward access to benzo-annulated nitrogen or oxygen heterocycles
Yoshida, Hiroto,Fukushima, Hiroyuki,Morishita, Takami,Ohshita, Joji,Kunai, Atsutaka
, p. 4793 - 4805 (2007)
A variety of aldehydes, ketones, benzoquinones, or sulfonylimines were found to couple with arynes and isocyanides, giving iminodihydroisobenzofuran or iminoisoindoline derivatives of structural diversity in a straightforward manner. Nucleophilic addition