Coumarin-enaminoester adducts: Structure corrections (X-ray) and some novel transformations. Synthesis of annulated tricyclic 2-pyridones
By means of X-ray crystallographic analysis the correct structure of all three types of stable coumarin-enaminoester adducts 6,10 and 11 and the corresponding spontaneous multistep heterocyclizations of ANRORC-type are reported. The initially formed adduc
Synthesis of some 6-alkylureido-4-aryl- 2(1H)-pyridones: Fürther transformations and pharmacological activity
The Michael addition of enaminoesters to coumarins (1) does not lead to the formation of simple adducts 3 but to the rearranged 4-aryl-2-pyridone 4a. Now, N-carbamoylation of the 6-amino-2-pyridone 4a with alkyl isocyanates and further transformation of t
Raev, Lyubomir Dimitrov,Ivanov, Ivo Christov,Astroug, Henri Angel,Frey, Wolfgang,Agontseva, Silviya Georgieva